Sveti Irenej rođen je najvjerojatnije u Smirni, u Maloj Aziji, sredinom 2. stoljeća. Ondje je, kao mladić, slušao svetog Polikarpa. Kasnije se preselio u Galiju gdje je, nakon smrti tamošnjeg biskupa Potina, bio izabran za lionskog biskupa. Prema predaji, umro je 202. godine. Papa Franjo proglasio
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